tag:blogger.com,1999:blog-28543539.post115315129282546559..comments2023-09-20T11:15:28.673+01:00Comments on Transform Drug Policy Foundation Blog: Daily Mail Science Proves Cannabis is a Gateway to Harder Drugsjanehttp://www.blogger.com/profile/15263261726046054614noreply@blogger.comBlogger2125tag:blogger.com,1999:blog-28543539.post-1153408409009533852006-07-20T16:13:00.000+01:002006-07-20T16:13:00.000+01:00If the rats accustomed to THC required larger dose...If the rats accustomed to THC required larger doses of heroin to be satisfied than controls, does that not imply that cannabis increases tolerance to heroin? <BR/><BR/>If cannabis increases tolerance to heroin, then, pharmacologically, cannabis users are less likely to become heroin addicts than<BR/>non-cannabis users, yes?Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-28543539.post-1153165220662964712006-07-17T20:40:00.000+01:002006-07-17T20:40:00.000+01:00Rats given THC in adolescent years were more likel...<I>Rats given THC in adolescent years were more likely to self-administer large quantities of heroin than rats which were not given THC during adolescence.</I><BR/><BR/>Actually, this study neither proves the gateway, nor 'increased use' either. <BR/><BR/>Both group of rates took the same amount of time to get started on heroin. The control group were more sensitive to heroin i.e. got similarly high with a smaller dose. Both groups became equally addicted, but the THC group stablilized on a higher maintenance dose as they were less sensitive, hence "more likely to self-administer large quantities of heroin".<BR/><BR/>Here's an <A HREF="http://sciencenow.sciencemag.org/cgi/content/full/2006/706/1" REL="nofollow">interview</A> with the lead author in ScienceNOW.<BR/><BR/>This image shows what happened when the rats were disconnected from the lever:<BR/><BR/><A HREF="http://www.nature.com/npp/journal/vaop/ncurrent/images/1301127f5.gif" REL="nofollow">Graph</A>.<BR/><BR/>The control group was more eager to get the drug source back!daksyahttps://www.blogger.com/profile/05473145703382086749noreply@blogger.com